Endocrine Abstracts

Thyroid nodules were frequently incidentally discovered during radiologic studies of chest or neck. We investigated the prevalence and clinical importance of thyroid incidentaloma during carotid artery ultrasonography in patients with diabetes. We retrospectively reviewed the data of enrolling all diabetic patients who were performed carotid artery ultrasonography at the Diabetes Center of Wonju Severance Christian Hospital from January to December 2013. Chart reviews of all e...

Introduction: haemangiopericytoma is a rare soft tissue tumour originating from pericytes. These are often large and slow growing tumours and manifest rarely as hypoglycaemia. We report a case of haemangiopericytoma-induced hypoglycaemia.Case report: A 72-year-old lady presented with an episode of confusion. She had had similar episodes usually in the early morning hours. She was also known to have hypertension and a large bladder haemangio...

Objective: The purpose of this study is to evaluate and compare the effectiveness of artificial intelligence-based computer-assisted diagnosis (AI-CAD) in diagnosing thyroid malignancy by inexperienced physicians and experienced radiologist.Methods: A total of 201 thyroid nodules from 192 patients was simultaneously evaluated by physician and radiologist using real-time ultrasound. After implementing AI-CAD, they reassessed the thyroid nodules. If necess...

Objectives: The macrofollicular variant of papillary thyroid cancer (MFV-PTC) is a rare subtype often lending to a challenging diagnosis. This study evaluated the ultrasonographic (US) features and clinical implication of MFV-PTC.Methods: Records of 14 patients histologically diagnosed with MFV-PTC at our institution over a period of 16 years were retrospectively reviewed. Preoperative US features, Bethesda categories determined by fine-needle aspiration...

Purpose: To evaluate the technical feasibility, efficacy, and safety of the anterolateral hydrodissection (ALHD) technique in radiofrequency ablation (RFA) for benign thyroid nodules.Methods: Between November 2019 and April 2020, 39 patients underwent 41 sessions of RFA with ALHD technique for treatment of benign thyroid nodules. ALHD was performed with cold (0°C–4°C) 5% dextrose solution during RFA to minimize pain and secure sufficient s...

Sclerotic bone lesions are a rare cause of hypocalcaemia. Calcium and vitamin D malabsorption are recognised complications of gastric bypass surgery. We describe the case of a 45 year-old woman with severe persistent symptomatic hypocalcaemia secondary to metastatic breast cancer, complicated by a previous Roux-en-Y gastric bypass, and the development of hypoparathyroidism. Her corrected calcium levels fell repeatedly and precipitously despite treatment with up to 8g/day oral ...

Background: Unlike excellent prognosis of classical papillary thyroid carcinoma (cPTC), certain pathological subtypes of aggressive variants of PTC (AV-PTC) are considered to have poor clinical outcome. However, the evidence of unfavorable outcome of AV-PTC is not clear because previous studies did not control other confounding factors contributed to clinical outcomes.Methods: This retrospective cohort study initially included 4339 patients with cPTC and...

Objectives: 18F-choline PET/CT is a recently introduced imaging modality to localize hyperfunctioning parathyroid glands in patient with hyperparathyroidism. But there has been no study according the diagnostic power of 18F-choline PET/CT in Korea so far owing to its limited distribution. Therefore, we evaluated the diagnostic performance of 18F-choline PET/CT in detection of hyperfunctioning parathyroid gland in patients with primary hyperpara...

Background: Characterisation of large adrenal lesion is challenging. There is no single robust imaging marker in defining benignity, especially for lesions which are greater than 4cm and are believed to carry increased risk of malignancy.A radiolabelled cholesterol analog tracer, I-131-Norcholesterol (NP-59), localises to adrenal cortical lesions. It has an established role in Conn’s syndrome. It is not expected to concent...

Introduction: Following treatment of Graves’ disease (GD), levels of thyrotropin receptor autoantibodies (TRAb) tend to decrease depending on treatment modality and length of follow up. We have assessed TRAb biological activity at follow up, years after GD treatment.Subjects and methods: TRAb concentration and biological activity were measured in 69 GD patients (59 females; 10 males; median age 59 years; TRAb positive at diagnosis), with follow up r...